The vasopeptidase inhibitor AVE7688 ameliorates Type 2 diabetic nephropathy
نویسندگان
چکیده
منابع مشابه
Nephroprotection by antifibrotic and anti-inflammatory effects of the vasopeptidase inhibitor AVE7688.
BACKGROUND Chronic renal disease substantially increases the risk of cardiovascular events and death. Vasopeptidase inhibitors are known to show a strong antihypertensive effect. In the present study, we investigated the nephroprotective potential of the vasopeptidase inhibitor AVE7688 beyond its antihypertensive effects in a mouse model of progressive renal fibrosis. METHODS COL4A3 -/- mice ...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2004
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-003-1264-8